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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Full frame distilled prediction
Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
- Candidate categories
- Meta-epidemiology (narrow)
- Consensus categories
- none
- Domain
- Candidate signal: noneConsensus signal: none
- Study design
- Candidate signal: ObservationalConsensus signal: none
- Genre
- Candidate signal: EmpiricalConsensus signal: Empirical
- Teacher disagreement score
- 0.584
- Threshold uncertainty score
- 1.000
- Validation status
machine_predicted_unvalidated·codex-gemma-dda1882f352a
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Opus teacher head0.017
GPT teacher head0.278
- Teacher spread
- 0.260 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
The record
- Venue
- Nature Genetics
- Topic
- Genetic Associations and Epidemiology
- Field
- Biochemistry, Genetics and Molecular Biology
- Canadian institutions
- Lunenfeld-Tanenbaum Research InstituteMcMaster UniversityOntario Institute for Cancer Research
- Funders
- National Cancer InstituteNational Human Genome Research InstituteNational Heart, Lung, and Blood InstituteAustralian Research CouncilEconomic and Social Research CouncilNational Institutes of HealthHeinz Nixdorf StiftungProvincia autonoma di Bolzano - Alto AdigeDiabetestutkimussäätiöHjartaverndNovo Nordisk FondenPaavo Nurmen SäätiöMedical Research CouncilTartu ÜlikoolSvenska KulturfondenOrionin TutkimussäätiöGöteborgs LäkaresällskapSydäntutkimussäätiöSamfundet FolkhälsanEmil Aaltosen SäätiöVetenskapsrådetNational Institute on Alcohol Abuse and AlcoholismStockholms Läns LandstingPäivikki ja Sakari Sohlbergin SäätiöCentre for Medical Systems BiologyNovo NordiskMinistero della SaluteNational Institute of Diabetes and Digestive and Kidney DiseasesTurun Yliopistollinen KeskussairaalaKnut och Alice Wallenbergs StiftelseNational Institute of General Medical SciencesNational Alliance for Research on Schizophrenia and DepressionNierstichtingBritish Heart FoundationBundesministerium für Bildung und ForschungEuropean Regional Development FundTerveyden ja hyvinvoinnin laitosAcademy of FinlandErasmus Medisch CentrumVrije Universiteit AmsterdamStiftelsen för Strategisk ForskningUniversitair Medisch Centrum GroningenDiabetes FondsNational Science FoundationFondation LeducqAgence Nationale de la RechercheHjärt-LungfondenRoyal SocietyAgency for Science, Technology and ResearchHelmholtz Zentrum MünchenMarch of Dimes FoundationKelaSvenska LäkaresällskapetDeutsche ForschungsgemeinschaftEuropean Science FoundationFondation pour la Recherche MédicaleSvenska Sällskapet för Medicinsk ForskningSocialdepartementetEuropean CommissionNHS Blood and TransplantFolkhälsanin TutkimussäätiöNational Institute for Health and Care ResearchWellcome TrustCancer Research UKMinistero dell’Istruzione, dell’Università e della RicercaQIMR Berghofer Medical Research InstituteScottish GovernmentYrjö Jahnssonin SäätiöCancerfondenFinska LäkaresällskapetFoundation for Cardiovascular ResearchDivision of Cancer Epidemiology and Genetics, National Cancer InstituteJuvenile Diabetes Research Foundation InternationalSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungTampereen TuberkuloosisäätiöRijksuniversiteit GroningenTorsten Söderbergs StiftelseKarolinska InstitutetNational Health and Medical Research CouncilSuomen KulttuurirahastoCedars-Sinai Medical CenterSigne ja Ane Gyllenbergin SäätiöGlaxoSmithKlineDonald W. Reynolds FoundationJuho Vainion SäätiöSusan G. Komen for the Cure
- Keywords
- BiologyGenetic architectureGeneticsGenome-wide association studyGenomeComputational biologyQuantitative trait locusMeta-analysisEvolutionary biologyGeneGenotypeSingle-nucleotide polymorphism
- Has abstract in OpenAlex
- no