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FES kinases are required for oncogenic FLT3 signaling

2010· article· en· 33 citations· W1992419413 on OpenAlex· 10.1038/leu.2009.301

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: fund_new · design weight: 1678.90 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

FES kinases in oncogenic FLT3 signaling; cancer cell biology.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: low

The title indicates a cancer-biology study, not research itself, but the abstract is missing.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: high

Biomedical paper on FES kinases in oncogenic FLT3 signaling; title is unambiguous domain biology.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Leukemia
Topic
Multiple Myeloma Research and Treatments
Field
Medicine
Canadian institutions
Funders
Institut National Du CancerFondation de FranceLigue Contre le CancerInstitute of Cancer ResearchInstitut National de la Santé et de la Recherche Médicale
Keywords
KinaseReceptor tyrosine kinaseCancer researchHaematopoiesisBiologyFms-Like Tyrosine Kinase 3Myeloid leukemiaTyrosine kinaseCellCell cycleCell biologySignal transductionMutationStem cellGeneticsGene
Has abstract in OpenAlex
no