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Record W1993132442 · doi:10.1080/02772240801937370

An exploratory study of chemical elements in drinking water and non-Hodgkin's lymphoma

2008· article· en· W1993132442 on OpenAlex
Manisha Witmans, Helen H. McDuffie, Chandima Karunanayake, R. Kerrich, Punam Pahwa

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueToxicological & Environmental Chemistry Reviews · 2008
Typearticle
Languageen
FieldSocial Sciences
TopicEnvironmental Justice and Health Disparities
Canadian institutionsStollery Children's HospitalUniversity of SaskatchewanUniversity of Alberta HospitalAlberta Hospital Edmonton
FundersSaskatchewan Cancer Agency
KeywordsEnvironmental chemistryCadmiumMetalloidArsenicChemistryWater qualityToxicologyContaminationEnvironmental science

Abstract

fetched live from OpenAlex

Previous studies reported associations of non-Hodgkin's lymphoma (NHL) with agriculture, agricultural practices, herbicide, and insecticide exposure. McDuffie et al. (McDuffie, H.H., P. Pahwa, and D.F. White. 1995. Saskatchewan women and agricultural exposures: any relationship to tumor incidence? In Agricultural Health and Safety: Workplace, Environment, Sustainability, ed. HH McDuffie, JA Dosman, KM Semchuk, S.A. Olenchock, and A. Senthilselvan, 135–42. Boca Raton, FL: CRC Press, Lewis Publishers) demonstrated a significantly higher risk of NHL associated with drinking water from shallow as compared to deep wells among women in Saskatchewan. Contamination of drinking water derived from groundwater sources may be due to natural sources and/or to the widespread use of pesticides and agricultural chemicals which may contain heavy metals and other elements as active ingredients. A NHL case (n = 88) – control (n = 132) study of drinking water quality was conducted by questionnaire, and by measuring the concentrations of 64 chemical elements simultaneously in drinking water samples utilizing inductively coupled plasma mass spectrometry technology. These data are reported either as geometric means or log-transformed because of skewness. Independent two sample t-test was used to compare the concentrations of each chemical element in samples of drinking water obtained from the homes of cases and controls. The chemical elemental analysis revealed statistically significant case/control differences in concentrations of 15 chemical elements versus three expected based on chance. Elements for which the concentrations in case/control drinking water samples differed were: lithium, boron, aluminum, silicon, phosphorus, titanium, cobalt, arsenic, selenium, yttrium, zirconium, cadmium, cesium, gadolinium, and uranium. The mean aluminum concentration was higher in water taken from the homes of controls compared to case homes, while the reverse occurred for the other 14 elements, with statistically significant differences in concentration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.180
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.049
GPT teacher head0.317
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it