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Record W1993240151 · doi:10.1086/521749

The Chimera of Liberal Individualism: How Cells Became Selves in Human Clinical Genetics

2007· article· en· W1993240151 on OpenAlexaff
Aryn Martin

Bibliographic record

VenueOsiris · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPluripotent Stem Cells Research
Canadian institutionsYork University
Fundersnot available
KeywordsIndividualismChimera (genetics)BiologyPoliticsPopulationSociologySubject (documents)EpistemologyEnvironmental ethicsGeneticsPolitical scienceLawPhilosophyGene

Abstract

fetched live from OpenAlex

Using Ian Hacking's notion of "making up people", this paper argues that human chimeras--people who contain more than one genetically distinct cell population--have been made up. As with multiple personality, the discourse surrounding the phenomenon of chimerism offers a novel vantage point for examining the socio-political processes of subject formation. Evidence from archives, interviews with cell scientists, and popular sources will show that, in a strange leap that has come to seem self-evident, journalists, laypeople, and even scientists have come to equate genomes with selves and hence conclude that chimeras are more than one person. Thus far, the challenge that chimeras pose to the simple alignment of genome-body-person has been limited both by relegating chimeras to freak show status and by liberal institutions' demands that individuals be singular.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.992
Threshold uncertainty score0.083

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0160.015
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0080.080
Scholarly communication0.0100.008
Open science0.0010.009
Research integrity0.0020.005
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.344
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations16
Published2007
Admission routes1
Has abstractyes

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