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BARRIERS TO THE SPREAD OF NEUTRAL ALLELES IN THE CYTONUCLEAR SYSTEM

2008· article· en· W1994032041 on OpenAlexaff
Xin‐Sheng Hu

Bibliographic record

VenueEvolution · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsBiologyAlleleBiological dispersalDisequilibriumGeneticsLinkage disequilibriumPloidyInheritance (genetic algorithm)Evolutionary biologyNon-Mendelian inheritancePollenHaplotypeMitochondrial DNAGenePopulationEcology

Abstract

fetched live from OpenAlex

Neutral alleles can eventually pass a hybrid zone and their initial clines generated by a pure diffusion process dissipate with time, irrespective of the presence or absence of physical barriers. However, the transient neutral clines at the nuclear or organelle sites can be reinforced by the cytonuclear disequilibrium generated by diploid seed and haploid pollen dispersal. In this study, the spread of a neutral allele in an ecological zone of hermaphrodite plants is examined under three cytonuclear systems for genomes with contrasting modes of inheritance (paternal, maternal, and biparental inheritance). The results show that the transient neutral clines can exhibit the spatial pattern similar to the selective clines from separate genomes although discordance between them exists. The spread of a neutral allele is not only related to the vectors of seed and pollen dispersal but also to the mode of its inheritance. Pollen dispersal facilitates the direct effects of the selective organelle sites with paternal inheritance on the spread of a neutral nuclear allele. It also enhances its indirect effects on the spread of a neutral organelle allele with maternal inheritance via modifying the cytonuclear disequilibrium. A positive relationship exists between the barriers to the spread of selective nuclear (or organelle) and neutral organelle (or nuclear) alleles. An asymmetric barrier to the spread of the neutral alleles exists on the two sides of the physical barrier, given the presence of symmetric barrier to the spread of the selective alleles. These theoretical predictions highlight the effects of cytonuclear disequilibrium on the spread of a neutral allele and draw attention to our empirical cline analysis with neutral markers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.749
Threshold uncertainty score0.176

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.213
Teacher spread0.207 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2008
Admission routes1
Has abstractyes

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