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Mechanisms of renal disease in indigenous populations: influences at work in Canadian indigenous peoples

2001· article· en· W1994729142 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueNephrology · 2001
Typearticle
Languageen
FieldMedicine
TopicPrenatal Substance Exposure Effects
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsIndigenousMedicineEnd stage renal diseaseDiseaseDiabetes mellitusPopulationDemographyStage (stratigraphy)GerontologyEnvironmental healthInternal medicineEndocrinology

Abstract

fetched live from OpenAlex

SUMMARY: Canadian aboriginal people experience end‐stage renal disease at rates 2.5–4 times higher than those found in the general population. Up to 60% of cases are due to diabetic end‐stage renal disease, while most of the remainder are caused by a variety of types of glomerulonephritis. The greatest increase in cases of end‐stage renal disease among aboriginal people since 1981 has been observed in those with diabetes. There appear to be three major contributing influences to the increase in diabetic end‐stage renal disease among Canadian aboriginal people. First, the rates of type 2 diabetes mellitus have increased from virtually zero to several times those seen in the general population in less than 60 years. Second, aboriginal people with diabetes have seven times the rate of diabetic end‐stage renal disease compared with their non‐aboriginal counterparts. Finally, birth rates among aboriginal people are higher than in any other segment of the population. An epidemic of diabetic end‐stage renal disease is the most important nephrological issue facing Canadian aboriginal people and threatens to overwhelm health care resources in many parts of the country unless effective early recognition and prevention programmes are established.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.745
Threshold uncertainty score0.820

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.256
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it