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Notch1 functions as a tumor suppressor in mouse skin

2003· article· en· 972 citations· W1995004385 on OpenAlex· 10.1038/ng1099

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.008
GPT teacher head0.253
Teacher spread
0.245 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Genetics
Topic
Hedgehog Signaling Pathway Studies
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
SickKids FoundationHospital for Sick ChildrenUniversity of Toronto
Funders
Keywords
BiologyNotch signaling pathwayCarcinogenesisCyclin-dependent kinase 8Notch proteinsCell biologyEpidermis (zoology)Cellular differentiationCancer researchSignal transductionTumor suppressor geneHes3 signaling axisCell fate determinationGeneGeneticsTranscription factorAnatomy
Has abstract in OpenAlex
no