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Record W1995389206 · doi:10.1080/21507740.2011.633962

Transforming Care Through Science: Evaluating the Impact and Implications of Neuromodulation in Psychiatric Populations

2012· article· en· W1995389206 on OpenAlexaff
Nir Lipsman, Andrés M. Lozano

Bibliographic record

VenueAJOB Neuroscience · 2012
Typearticle
Languageen
FieldMedicine
TopicNeurological disorders and treatments
Canadian institutionsToronto Western Hospital
Fundersnot available
KeywordsNeuromodulationTransformative learningDeep brain stimulationPsychologyNeurosurgeryPsychiatryQuality of life (healthcare)NeuroethicsPsychotherapistMental illnessDiseaseMedicineNeuroscienceMental healthDevelopmental psychologyParkinson's disease

Abstract

fetched live from OpenAlex

Current conceptions rightly view neurosurgery and deep brain stimulation as last-resort therapies in psychiatric disease. It is unclear, however, whether this should, or will, always be the case in the future. The impact and transformative potential of DBS will be judged by (i) its safety profile, (ii) the quality of life it provides previously debilitated patients, and (iii) by the knowledge gained, through its use, about the etiology and maintenance of both normal and abnormal brain functioning. Viewed in this way, few treatments in medicine, and certainly fewer in psychiatry and neurosurgery, have the potential to inform all of these, in as substantial and meaningful a way. Here we examine the transformative potential of neuromodulation technology, and argue in favor of a new chapter in the history of mental illness management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.073
Threshold uncertainty score0.218

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.119
GPT teacher head0.441
Teacher spread0.322 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

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