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Record W1997430748 · doi:10.1155/2013/205494

Robust Diffeomorphic Mapping via Geodesically Controlled Active Shapes

2013· article· en· W1997430748 on OpenAlexfundno aff
Daniel J. Tward, Jun Ma, Michael I. Miller, Laurent Younès

Bibliographic record

VenueInternational Journal of Biomedical Imaging · 2013
Typearticle
Languageen
FieldComputer Science
TopicMedical Image Segmentation Techniques
Canadian institutionsnot available
FundersNational Institute of Neurological Disorders and StrokeNational Institute of Mental HealthNational Institute on AgingUniversity of California, San DiegoNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchUniversity of California, Los AngelesNational Institutes of HealthServierGenentechInnogeneticsEisaiNatural Sciences and Engineering Research Council of CanadaPfizerBiogenBioClinicaCanadian HIV Trials Network, Canadian Institutes of Health ResearchNorthern California Institute for Research and EducationAlzheimer's AssociationAmorfix Life SciencesNational Center for Research ResourcesF. Hoffmann-La RocheMedpaceAstraZenecaEli Lilly and CompanyBristol-Myers SquibbNational Heart, Lung, and Blood InstituteNovartis Pharmaceuticals CorporationSynarcBayer HealthCareAlzheimer's Disease Neuroimaging InitiativeMeso Scale DiagnosticsFoundation for the National Institutes of Health
KeywordsDiffeomorphismGeodesicComputer scienceMetric (unit)AlgorithmLandmarkArtificial intelligenceMathematicsGeometryMathematical analysis

Abstract

fetched live from OpenAlex

This paper presents recent advances in the use of diffeomorphic active shapes which incorporate the conservation laws of large deformation diffeomorphic metric mapping. The equations of evolution satisfying the conservation law are geodesics under the diffeomorphism metric and therefore termed geodesically controlled diffeomorphic active shapes (GDAS). Our principal application in this paper is on robust diffeomorphic mapping methods based on parameterized surface representations of subcortical template structures. Our parametrization of the GDAS evolution is via the initial momentum representation in the tangent space of the template surface. The dimension of this representation is constrained using principal component analysis generated from training samples. In this work, we seek to use template surfaces to generate segmentations of the hippocampus with three data attachment terms: surface matching, landmark matching, and inside-outside modeling from grayscale T1 MR imaging data. This is formulated as an energy minimization problem, where energy describes shape variability and data attachment accuracy, and we derive a variational solution. A gradient descent strategy is employed in the numerical optimization. For the landmark matching case, we demonstrate the robustness of this algorithm as applied to the workflow of a large neuroanatomical study by comparing to an existing diffeomorphic landmark matching algorithm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.002
Scholarly communication0.0010.002
Open science0.0020.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.265
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations21
Published2013
Admission routes1
Has abstractyes

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Same venueInternational Journal of Biomedical ImagingSame topicMedical Image Segmentation TechniquesFrench-language works237,207