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Record W1999259961 · doi:10.1136/bmj.e5081

Detection of bowel cancer in kidney transplant recipients

2012· letter· en· W1999259961 on OpenAlexaff
Paul Blaker, D. Goldsmith

Bibliographic record

VenueBMJ · 2012
Typeletter
Languageen
FieldMedicine
TopicColorectal Cancer Screening and Detection
Canadian institutionsSt. Thomas Hospital
Fundersnot available
KeywordsMedicineColorectal cancerPopulationDialysisKidney transplantationCancerColonoscopyInternal medicineEpidemiologyKidney cancerTransplantationObservational studyKidney diseaseIntensive care medicineOncology

Abstract

fetched live from OpenAlex

Can be achieved safely with colonoscopy screening Kidney transplantation is the only cure for progressive kidney failure that requires renal replacement by dialysis. This intervention is now very successful, but is limited by increased mortality associated with infection, cardiovascular disease, and cancer. One important cancer related cause of death in this population is colorectal cancer. In a linked research paper (doi:10.1136/bmj.e4657), Collins and colleagues study the prevalence of this cancer in kidney transplant recipients aged over 50 years and the diagnostic accuracy of colonoscopy screening in this population.1 Although deaths from colorectal cancer are starting to fall in the general population, probably because of greater public awareness and more systematic screening,2 kidney transplant recipients have a twofold increased risk of de novo colorectal cancer.3 4 5 These patients are often younger at diagnosis than those in the general population. Their five year survival rate was also significantly lower than for other patients with colorectal cancer in an observational study that used the National Cancer Institute Survival, Epidemiology and End Result (SEER) database.6 This worse prognosis is probably related to increased tumour aggressiveness, reduced …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.019
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.010
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.019
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0100.006
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.296
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2012
Admission routes1
Has abstractyes

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