Microfluidic device for simultaneous pulsed electric field electroporation and dielectrophoresis studies of single biological cells
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
We present a microfluidic device able to electroporate and measure the resultant changes in dielectric properties of single biological cells. The device can measure the dielectrophoresis (DEP) response of the electroporated cell from a few seconds after exposure to electroporating pulses. Studying electroporation at the single cell level can provide insight on the electroporation process as well as a method of differentiating cellular state (e.g. normal and cancerous). Moreover, combining electroporation and dielectric characterization into a single device eliminates the need for post-sample analysis as required in techniques such as fluorescence cytometry. Experiments performed on Chinese hamster ovary (CHO) cells demonstrate the ability of the device to detect changes in the DEP response of individual cells immediately after being exposed to microsecond duration electroporating pulses.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it