Effect of Secretin on the Secretion of Acid and Pepsin by the Totally Isolated Canine Stomach
Bibliographic record
Abstract
Totally isolated whole canine stomachs, perfused ex vivo with homologous blood, were used for study of the action of secretin on gastric secretion of acid and pepsin. During 8 h of perfusion, stomachs were stimulated by constant infusion of pentagastrin, 32 μg/h, into gastric arteries of isolated organs. When base line secretion was established (3.5 h), secretin, 60 U/h, was also infused for 90 min into the gastric artery. Secretin injection was then interrupted, but pentagastrin infusion continued until the termination of the experiment. Secretin reduced the volume of secretion and the concentration and output of HC1. Secretin also increased the concentration and output of pepsin. Dissociated effect of secretin on gastric acid and pepsin secretion by totally isolated in vivo perfused canine stomachs resembles the action of secretin on gastric secretion, reported by others, in various in vivo experiments.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".