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Interaction between organ mass and citrate synthase activity as an indicator of tissue maximal oxidative capacity in breeding European Starlings: implications for metabolic rate and organ mass relationships

2005· article· en· W2000644763 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueFunctional Ecology · 2005
Typearticle
Languageen
FieldEnvironmental Science
TopicPhysiological and biochemical adaptations
Canadian institutionsSimon Fraser University
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBiologyCitrate synthaseKidneyInternal medicineOxidative phosphorylationEndocrinologyBasal metabolic ratePhysiologyEnzymeBiochemistry

Abstract

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Summary Numerous studies have suggested that basal metabolic rate (BMR) is related to variation in mass of specific ‘energy‐expensive’ organs such as heart and kidney. However, there are inconsistencies among studies with regard to those organs that show positive relationships with BMR, potentially because such studies assume constant organ metabolic intensity or capacity (e.g. oxidative activity). This paper investigates metabolic adjustments (citrate synthase activity) in four key organs (pectoral muscle, heart, kidney and liver) in free‐living reproductive female European Starlings ( Sturnus vulgaris ) throughout the breeding season to determine if the cost of egg production results in readjustments in organ mass‐specific enzyme activity. Citrate synthase (CS) activity varied in relation to breeding stage and/or year, but this variation was not consistent among different organs. For some organs, total enzymatic activity was directly related to changes in organ mass in relation to breeding stage. For others, increased organ mass was associated with a decrease in mass‐specific CS activity, resulting in no net change in total organ oxidative capacity among breeding stages. Even though the liver is actively involved in yolk precursor production during egg formation, no evidence was found for up‐regulation of mass‐specific oxidative enzyme activity in this organ. Metabolic adjustments at the organ level may occur independently from organ mass changes and this confounding effect may be responsible for part of the inconsistencies found between previous studies in terms of organs mass–RMR relationships.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.823
Threshold uncertainty score0.410

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.263
Teacher spread0.201 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it