Acrosin activity in pelleted frozen sperm does not correlate with in vitro fertilization of oocytes
Why this work is in the frame
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Bibliographic record
Abstract
Spermatozoa pelleted after swim-up were frozen and then analysed in batches for acrosin activity, using a spectrophotometric method, and expressed as microIU micrograms DNA-1. A total of 259 sperm samples were analysed and the acrosin activity compared with fertilization in vitro. Of these, 224 samples fertilized at least one oocyte and 35 samples failed to fertilize any oocyte. Analysis by Student's t-test indicated that there was a statistically significant difference (P = 0.02) in acrosin activity between the two groups. However, when samples that failed to fertilize were matched for concentration, motility and normal morphology with samples that fertilized, this significance was lost (P = 0.77). It is concluded that total acrosin in pelleted sperm frozen after regular swim-up, does not correlate with fertilizing ability of spermatozoa used for insemination.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it