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Record W2001551999 · doi:10.1159/000233645

Isolation and Characteristics of Small Intestinal Lamina Propria Cells from Normal and Nematode (Nippostrongylus brasiliensis)-Infected Rats

2009· article· en· W2001551999 on OpenAlexaff
A. Dean Befus, John Spencer, Mark R. McDermott, Barney McLaughlin, John Bienenstock

Bibliographic record

VenueInternational Archives of Allergy and Applied Immunology · 2009
Typearticle
Languageen
FieldVeterinary
TopicHelminth infection and control
Canadian institutionsMcMaster University
Fundersnot available
KeywordsNippostrongylus brasiliensisBiologyLamina propriaConcanavalin AThymidineImmunologyEndocrinologyUridineInternal medicineHistamineImmune systemEpitheliumIn vitroBiochemistryMedicine

Abstract

fetched live from OpenAlex

Intestinal lamina propria (LP) cells were isolated from normal or nematode (Nippostrongylus brasiliensis)-infected rats. At certain times after infection (days 11-17), viable cell recoveries from infected rats were lower, whereas at other times (days 20-50), they were significantly greater than those from normal rats. The frequencies of lymphocytes, plasma cells, eosinophils, mast cells and macrophages from LP differed between normal and infected rats, and the histamine content did also. However, spontaneous 3H-uridine and 3H-thymidine incorporation and the number of cells with cytoplasmic immunoglobulin were similar. LP cells from normal rats were unresponsive to the mitogens phytohemagglutinin, concanavalin A and pokeweed. 125I-deoxyuridine-radiolabeled LP lymphoblasts from normal rats were widely distributed in recipients 22-24 h after transfer and showed no selective predilection to return to the intestine. The isolation procedure can be used to study intestinal LP cells from normal or diseased animals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.947
Threshold uncertainty score0.572

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.234
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2009
Admission routes1
Has abstractyes

Explore more

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