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Record W2001598409 · doi:10.2533/000942905777675660

In-Strand Metallated Nucleic Acids – Novel Bioinorganic Constructs

2005· article· en· W2001598409 on OpenAlexfundno aff
Edwin C. Constable, Valérie Chaurin, Catherine E. Housecroft, Amina Wirth

Bibliographic record

VenueCHIMIA International Journal for Chemistry · 2005
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDNA and Nucleic Acid Chemistry
Canadian institutionsnot available
FundersUniversity of BernEuropean Social FundSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungCanada Excellence Research Chairs, Government of CanadaUniversität BaselNational Science Foundation
KeywordsOligonucleotideBioinorganic chemistryNucleic acidChemistryMetalCombinatorial chemistrySequence (biology)StereochemistryComputational biologyBiochemistryDNABiologyOrganic chemistry

Abstract

fetched live from OpenAlex

Synthetic strategies have been developed for the preparation of in-chain metallated oligonucleotides, in which the oligonucleotide sequence is interrupted by a metal-containing motif. In our work, oligopyridine metal-binding domains are used and approaches are outlined using both labile and non-labile metal centres.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.125
Threshold uncertainty score0.918

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.262
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2005
Admission routes1
Has abstractyes

Explore more

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