Aggregation and Adsorption of Type I Collagen near an Electrified Interface
Bibliographic record
Abstract
An electric field can stimulate collagen fibrillogenesis in an acidic electrolyte, while unaggregated collagen monomers are preferentially adsorbed to the electrified interface itself. These effects are demonstrated using a Hull cell to apply an electric current gradient to 0.01 M HCl or 0.01 M HNO 3 containing collagen monomers. Atomic force microscopy and Raman scattering spectroscopy data show that collagen microfibrils form in the electrolyte and migrate toward the negatively charged working electrode. However, collagen monomers adsorb to the working electrode due in part to their faster electromigration rates. Despite the dramatic pH difference between the acidic bulk electrolyte (pH = 2) and the basic diffusion layer region in the immediate vicinity of the working electrode surface (pH > 10) due to base electrogeneration reactions in the aqueous electrolytes, there is no evidence that the electroadsorbed collagen monomers suffer from the effects of denaturation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".