Scorpion model of influenza A/H1N1: Hemagglutinin (HA) contains a scorpion toxin, binding to voltage-gated sodium Na+ channel: Na+ channel inhibitors as therapy
Bibliographic record
Abstract
Despite therapeutic progress in receptor binding inhibition, some deaths continue to occur, especially in young people. We try to find new approaches to fight against Influenza virus resistance. We were interested in Guillain-Barré syndrome (GBS) during the 1976 US vaccination campaign, because Breurec JY in France described a case of GBS after a scorpion sting by a Centruroides noxius species. We compared amino acid sequences of Influenza virus A/H1N1 with scorpion venom toxins. The cysteine-rich region (56-109) with C59, C72, C84, C107 was aligned in 3 dimensions with scorpion toxin Figure 1 . Figure 1 a) HA of pandemic Influenza virus A/H1N1 2009 Mexico (466-VKEYI-462) [ACY77964], Canada-AB (56-109), Japan (246-YYWKLV-251) HA of pandemic Influenza virus A/H1N1 2009 Mexico (466-VKEYI-462) [ACY77964], Canada-AB (56-109), Japan (246-YYWKLV-251) b) scorpion toxin (AaH II/Cn II-13 VKEGYI) (AaH IT4 YFWKLA) scorpion toxin (AaH II/Cn II-13 VKEGYI) (AaH IT4 YFWKLA)
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".