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Record W2004907773 · doi:10.1159/000131866

Heterochromatin heterogeneity in Chinese hamster sex bivalents

2008· article· en· W2004907773 on OpenAlex
M. Murer‐Orlando, C.-L. Richer

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCytogenetics and Cell Genetics · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsHeterochromatinBiologyBivalent (engine)ChiasmaGiemsa stainHomologous chromosomeChinese hamsterMeiosisGeneticsSatellite DNACentromereMolecular biologyDNAChromosomeChromatinGeneChemistry

Abstract

fetched live from OpenAlex

The heterochromatin of the Chinese hamster sex chromosomes was analyzed by different banding techniques. Combined results obtained after differential Ba(OH)2 treatment, BrdU incorporation, Giemsa 11, and staining with quinacrine permitted the characterization of different regions in the heterochromatic portions of the X and Y chromosomes. In the light of these observations, the chiasma observed in the sex bivalent of Chinese hamster spermatocytes was localized within specific heterochromatic regions. The homologous segments consist of the entire short arm of the Y and the distal end of the long arm of the X up to band q21. These regions are probably not rich in highly repetitive DNA sequences, which are more resistant to alkali denaturation, or in satellite DNA, which is stained by Giemsa 11. Thus the heterochromatin in the homologous regions of the sex chromosomes allows the formation of a chiasma. The heterogeneity found in these heterochromatic regions may help to establish a more precise relationship between heterochromatin and recombination.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.343
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.260
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it