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Record W2005077186 · doi:10.4021/jmc.v5i2.1661

Multiple Arthralgia After Use of Amoxicillin in EBV Infection: Could it be Adult Onset of Still’s Disease?

2014· article· en· W2005077186 on OpenAlexvenueno aff
Rachel WC Ng, Chi Eung Danforn Lim, Nga Chong Lisa Cheng

Bibliographic record

VenueJournal of Medical Cases · 2014
Typearticle
Languageen
FieldMedicine
TopicAutoimmune and Inflammatory Disorders Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineRashAdult-onset Still's diseasemyalgiaDiseaseAmoxicillinDermatologyImmunologyInternal medicineAntibiotics

Abstract

fetched live from OpenAlex

This case discusses about a rare development of adult-onset of still’s disease in a 39-year-old male patient after taking amoxicillin for 14 days in an upper respiratory infection setting. It was confirmed later that he was in fact suffering from EBV infection at that time. Adult Onset Still ’ s Disease (AOSD) is a rheumatic disease that tends to affect young adults between the ages of 16 and 35. This article presents an uncommon case of AOSD after use of amoxillcin with EBV infection. Still’s disease is thought to be triggered by external infectious agents in genetically predisposed hosts, with many clinical manifestations of AOSD similar to those of self-limited viral infections. Major clinical manifestations include transient fever, rash, arthralgia and arthiritis, myalgia and liver abnormalities. Diagnosis of AOSD is typically based on clinical observation. Treatment for AOSD is empirical and centers on the use of NSAIDs, steroids and disease modifying anti-rheumatic drugs. J Med Cases. 2014;5(2):105-107 doi: http://dx.doi.org/10.14740/jmc1661w

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.003
Open science0.0010.001
Research integrity0.0040.002
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.330
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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