Functional Architecture and Spike Timing Properties of Corticofugal Projections From Rat Ventral Temporal Cortex
Bibliographic record
Abstract
Sensory association and parahippocampal cortex in the ventral temporal lobe plays an important role in sensory object recognition and control of top-down attention. Although layer V neurons located in high-order cortical structures project to multiple cortical and subcortical regions, the architecture and functional organization of this large axonal network are poorly understood. Using a large in vitro slice preparation, we examined the functional organization and spike timing properties of the descending layer V axonal network. We found that most, if not all, layer V neurons in this region can form multiple axonal pathways that project to many brain structures, both proximal and remote. The conduction velocities of different axonal pathways are highly diverse and can vary up to more than threefold. Nevertheless for those axonal projections on the ipsilateral side, the speeds of axonal conduction appear to be tuned to their length. As such, spike delivery becomes nearly isochronic along these pathways regardless of projection distance. In contrast, axons projecting to the contralateral hemisphere are significantly slower and do not participate in this lateralized isochronicity. These structural and functional features of layer V network from the ventral temporal lobe may play an important role in top-down control of sensory cue processing and attention.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".