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Record W2005905131 · doi:10.1177/1420326x04047764

Coalinga Chrysotile: A Short-Fibre, Amphibole-Free, Chrysotile: Part VI - Additional Evidence for Lack of Fibrogenicity

2004· article· en· W2005905131 on OpenAlexaboutno aff
E.B. Ilgren

Bibliographic record

VenueIndoor and Built Environment · 2004
Typearticle
Languageen
FieldMedicine
TopicOccupational and environmental lung diseases
Canadian institutionsnot available
FundersMedical Research Council
KeywordsChrysotileMaterials scienceAsbestosMetallurgy

Abstract

fetched live from OpenAlex

This report describes additional unpublished data that support the notion that Coalinga chrysotile is not fibrogenic. These data are from the same long-term, NTP-NIEHS, chronic chrysotile inhalation study that served as the basis for our earlier publications which concluded that Coalinga chrysotile was not fibrogenic due to its lack of biopersistence. Wagner-scored 12 and 24 month interim sacrifice data from the NTP-NIEHS investigation and an unpublished data set from the comparison MRC study both previously unreported, were recently found in the author’s files. The histology slides and attendant data should have been amongst the materials archived at the NTP but were not present at the time the author reviewed those files in 1995 and 1996. Review of these new materials showed that Coalinga chrysotile did not produce fibrosis either at 12 or 24 months in contrast to the two Canadian preparations which were both fibrogenic even at this early stage of the study. These new data and related testimony greatly strengthen our earlier conclusions and serve to refute earlier apparently contradictory reports. International and Governmental Reports support the conclusion reached in our papers that Coalinga chrysotile is not pathogenic. In fact, the only scientists to criticise our conclusions have been in litigation against Union Carbide.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.131
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.324
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2004
Admission routes1
Has abstractyes

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