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A map of rice genome variation reveals the origin of cultivated rice

2012· article· en· 1,701 citations· W2006066143 on OpenAlex· 10.1038/nature11532

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Abstract

Crop domestications are long-term selection experiments that have greatly advanced human civilization. The domestication of cultivated rice (Oryza sativa L.) ranks as one of the most important developments in history. However, its origins and domestication processes are controversial and have long been debated. Here we generate genome sequences from 446 geographically diverse accessions of the wild rice species Oryza rufipogon, the immediate ancestral progenitor of cultivated rice, and from 1,083 cultivated indica and japonica varieties to construct a comprehensive map of rice genome variation. In the search for signatures of selection, we identify 55 selective sweeps that have occurred during domestication. In-depth analyses of the domestication sweeps and genome-wide patterns reveal that Oryza sativa japonica rice was first domesticated from a specific population of O. rufipogon around the middle area of the Pearl River in southern China, and that Oryza sativa indica rice was subsequently developed from crosses between japonica rice and local wild rice as the initial cultivars spread into South East and South Asia. The domestication-associated traits are analysed through high-resolution genetic mapping. This study provides an important resource for rice breeding and an effective genomics approach for crop domestication research. Whole-genome sequences of wild rice and cultivated rice varieties are used to produce a map of rice genome variation, and show that rice was probably first domesticated in southern China. Cultivated rice (Oryza sativa) is thought to have been domesticated from wild rice (Oryza rufipogon) thousands of years ago. This Chinese/Japanese collaboration reports whole-genome sequences from 446 wild rice isolates from across Asia and Oceana, and from more than 1,000 indica and japonica subspecies of cultivated rice. The resulting map of genome variation will be an important resource for rice breeding and for crop-domestication research.

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The record

Venue
Nature
Topic
Genetic Mapping and Diversity in Plants and Animals
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Funders
Institute of GeneticsNational Natural Science Foundation of ChinaChinese Academy of SciencesMinistry of Education, Culture, Sports, Science and Technology
Keywords
DomesticationOryza rufipogonOryza sativaBiologyOryzaJaponicaGenomePopulationCropGenomicsBotanyAgronomyGeneticsGene
Has abstract in OpenAlex
yes