Immunomodulatory Activity of Polysaccharide from the Roots of Actinidia kolomikta on Macrophages
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Actinidia kolomikta is a species of wild plant that grows wildly in the northern part of Indochina. However there are no reports about its immunomodulatory activity. In this study, the immunomodulatory activities of crude polysaccharide (CP) fraction from the root of Actinidia kolomikta on macrophage RAW 264.7 cells were investigated. Results showed that treatment with 2.5-25 µg/ml of CP stimulated macrophage proliferation, nitric oxide production and phagocytosis in a dose-dependent manner. Treatment with 5 µM Doxorubicin (DOX) resulted in macrophages survival rate decrease (12.6%). However co-incubation with 25 µg/ml of CP, the DOX-induced macrophage survival rate was 89.8%. At the same time the apoptosis of macrophage decreased from 37.8% (5 µM DOX) to 21.5% (co-incubation with 10 µg/ml of CP). It is suggested that CP possesses immunomodulatory activity on macrophages and protects macrophages from DOX damage.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it