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Record W2007060992 · doi:10.1097/hco.0b013e32831217ed

Predicting outcomes in cardiac surgery: risk stratification matters?

2008· review· en· W2007060992 on OpenAlexafffund
Jean‐Yves Dupuis

Bibliographic record

VenueCurrent Opinion in Cardiology · 2008
Typereview
Languageen
FieldMedicine
TopicCardiac Valve Diseases and Treatments
Canadian institutionsUniversity of Ottawa
FundersUniversity of Ottawa
KeywordsMedicineLogistic regressionPerioperativePredictive modellingRisk stratificationIntensive care medicineRisk assessmentActuarial scienceSurgeryStatisticsInternal medicine

Abstract

fetched live from OpenAlex

PURPOSE OF REVIEW: To illustrate the limitations of predictive risk models in cardiac surgery, highlight the difficulty in interpreting risk-adjusted outcome analysis and discuss the challenges of making clinical decisions based on risk predictions, particularly in high-risk patients. RECENT FINDINGS: Predictive risk models developed after logistic regression or other complex statistical analysis are commonly perceived as rigorous means to determine risk-adjusted mortality in cardiac surgery. However, the discrimination provided by those predictive models is barely better than clinical judgment. Moreover, validation studies of those models show that their calibration is inconsistent, limiting their application for comparisons between different patient cohorts. Recent data also show that, without a reasonable overlap of case-mix distributions, apparently calibrated models used for risk-adjusted outcome analysis may lead to inaccurate side-by-side comparisons of provider performance. Finally, most predictive models overestimate risk, particularly in the high-risk patients. SUMMARY: Failure to account for many biological and procedural variables and for the constantly evolving practice of surgery and perioperative medicine likely contributes to the modest predictive performance of risk models in cardiac surgery. Consequently, those models should have limited input in the analysis of provider performance and in the decision to accept or deny surgery to the high-risk patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.568
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0050.005
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.105
GPT teacher head0.440
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations33
Published2008
Admission routes2
Has abstractyes

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