Bibliographic record
Abstract
泛素结合酶(E2)是泛素/26S蛋白酶体途径中三个关键酶之一,在靶蛋白识别、与泛素连接酶(E3)互作等蛋白的泛素依赖性水解和N-末端规则依赖性水解途径的关键环节中起重要作用。本研究采用Solexa测序技术获得了一条油茶E2的全长cDNA序列,命名为UBE2S,该基因编码270AA,与其它物种的E2具有较高的一致性和相似性,UBE2S蛋白具有泛素结合酶催化位点(UBCc),第13~145位氨基酸碱基为其泛素结合酶基因家族的保守区域,第79~127位氨基酸残基区域中有21个残基与泛素形成硫酯键中间产物的残基,其中94位的半胱氨酸残基是活性位点,有5个残基是与E3酶相互作用的位点。UBE2S具有C端延伸结构,所以在普通油茶E2基因家族中属于Ⅱ类E2。
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.002 |
| Scholarly communication | 0.003 | 0.003 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.009 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".