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Efficacy of second generation antipsychotics in treating acute mixed episodes in bipolar disorder: A meta-analysis of placebo-controlled trials

2013· review· en· 47 citations· W2008258948 on OpenAlex· 10.1016/j.jad.2013.04.032

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Full frame distilled prediction

Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

Candidate categories
Meta-epidemiology (narrow), Meta-epidemiology (broad)
Consensus categories
Meta-epidemiology (broad)
Domain
Candidate signal: noneConsensus signal: none
Study design
Candidate signal: Meta-analysisConsensus signal: none
Genre
Candidate signal: ReviewConsensus signal: Review
Teacher disagreement score
0.540
Threshold uncertainty score
1.000
Validation status
machine_predicted_unvalidated · codex-gemma-dda1882f352a

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0200.011
Bibliometrics0.0040.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.086
GPT teacher head0.387
Teacher spread
0.301 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Journal of Affective Disorders
Topic
Bipolar Disorder and Treatment
Field
Medicine
Canadian institutions
University of British Columbia
Funders
not available
Keywords
ManiaZiprasidonePlaceboBipolar disorderBipolar I disorderInternal medicineMedicineAripiprazoleQuetiapineRisperidonePsychiatryYoung Mania Rating ScaleRandomized controlled trialAsenapineOlanzapineMoodSchizophrenia (object-oriented programming)
Has abstract in OpenAlex
no