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Record W2008516732 · doi:10.1117/12.447132

<title>Fluorescence spectroscopy and imaging for detection of colonic dysplasia</title>

2001· article· en· W2008516732 on OpenAlexaff
Norman E. Marcon

Bibliographic record

VenueProceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 2001
Typearticle
Languageen
FieldMedicine
TopicColorectal Cancer Screening and Detection
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsColonoscopyDysplasiaMedicineColorectal cancerEndoscopyGold standard (test)GastroenterologyCancerScarsWhite lightInternal medicinePathologyRadiology

Abstract

fetched live from OpenAlex

Cancer of the colon is the second leading cause of cancer related death in North America and Europe. Colonoscopy is currently the gold standard for the detection and removal of polyps and the diagnosis of cancer. Although a field of intense research, there are currently no surrogate serum or stool markers that accurately identify patients at risk who may have adenomatous colon polyps or curable cancer. Clinicians therefore rely on white light colonoscopy to survey colonic mucosa in their search for poiyps. White light endoscopy has some limitations. It cannot detect flat, non raised lesions. It cannot distinguish easily between hyperplastic and adenomatous polyps. Subtle, flat lesions may be missed. Scars at the sites ofprevious sessile polyps are difficult to evaluate for recurrence. Endoscopies utilizing fluorescence techniques either on the basis of intrinsic fluorescence or exogenous (prodrug) compounds, have the potential to compliment white light endoscopy by improving detection of mucosal dysplasia and ultimately improve outcomes for cancer detection before the date of escape from cure.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.042
Threshold uncertainty score0.141

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0420.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.239
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2001
Admission routes1
Has abstractyes

Explore more

Same venueProceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE→Same topicColorectal Cancer Screening and Detection→French-language works237,207→