Bibliographic record
Abstract
ELL strains well-adapted to permanent growth in tissue culture C are characterized by chromosome conditions essentially different from those of normal cells.Instead, they show striking resemblances with old transplantable tumors.Thus, their chromosome complement varies from cell to cell.These variations, involving both number and structure, fluctuate around one stemline karyotype, which usually differs from the normal karyotype of the species.These facts indicate that the cell strain genotype has undergone, during its history, a far-reaching reorganization making it well-adapted to the new life habit of growth in uitro.In the present work the chromosomes were studied in three human cell strains, two of which were of normal origin and the third of cancer origin.All three strains were grown serially at the tissue culture laboratory of the Institute of Bacteriology, Lund.The following strains were studied: 1. Fogh.This strain, established in March 1956 at the University of California, Berkeley, from human amnion (FOCH and LUND, 1957), has been carried at the Institute of Bacteriology, Lund, since March 1958.It has passed 120-150 transfers at Lund. 2.Parotis, started in October 1957 by Dr. SVEN BERGMAN from parotis glands of a five months old, male embryo, has gone through more than 50 passages (cf.BERGMAN, 1959, and BERGMAN, NILSSON andOLSSON, 1959).3. H , Ep. 1.This was an epidermoid carcinoma of the cervix of a 52 years old female.It was established in tissue culture in February 1953 at the Sloan-Kettering Institute, New York (FJELDE, 1955(FJELDE, , 1956)).This tumor exists in different strains.The strain studied by me was brought from Sloan-Kettering to Copenhagen in 1953 by Dr. FJELDE, 29" -Hereditas 4S CLAES NORRYD TOOLAN, H. W. 1953.Growth of human tumors in cortisone-treated laboratory animals: The possibility of obtaining permanently transplantable human tumors.-Cancer Research 13: 9 8 9 4 9 4 .-1954.Transplantable human neoplasms maintained in cortisone-treated labora.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.006 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".