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Reducing the effect of parent averages from animal solutions in mixed model equations

2000· article· en· W2009134064 on OpenAlex
Liangxuan Wu, L.R. Schaeffer

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueJournal of Animal Breeding and Genetics · 2000
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsUniversity of Guelph
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsInbreedingBest linear unbiased predictionHeritabilityStatisticsSelection (genetic algorithm)Animal modelMixed modelBiologyRestricted maximum likelihoodMathematicsEconometricsEvolutionary biologyPopulationDemographyComputer scienceMaximum likelihood

Abstract

fetched live from OpenAlex

Summary Selection of animals based on their BLUP evaluations from an animal model results in animals that are closely related which leads to increased rates of inbreeding. The tendency for higher inbreeding rates is greater at low heritability values. Several attempts have been made to reduce the impact of parent average breeding values from animals evaluations in order to reduce inbreeding while not sacrificing genetic response. A method that modifies the rules for forming the inverse of the additive genetic relationship matrix for use in best linear unbiased estimation of breeding values via an animal model was developed. This method and several others were compared analytically and empirically, from the perspective of partitioning the animal solutions into contributions from the data, from progeny, and from the parent average. The ratio of genetic progress to average level of inbreeding showed that the modified relationship matrix method was superior to the other methods. Similar results could be obtained by using artificially high heritability in a usual BLUP analysis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.766
Threshold uncertainty score0.321

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.260
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it