Corneal Myxoma Arising in a Patient With Repeated Phototherapeutic Keratectomies
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Bibliographic record
Abstract
PURPOSE: We report the clinical and pathologic findings of a corneal myxoma that was diagnosed in a cornea that had undergone phototherapeutic keratectomy (PTK). METHODS: A corneal myxoma was identified in a full-thickness keratoplasty specimen obtained from a 51-year-old man with a history of a forceps injury to his right eye at birth. The patient had presented with corneal edema and bullous keratopathy, which was treated on 3 occasions with PTK, resulting in progressive, persistent milky-white clouding of the cornea. This represents the eighth case of corneal myxoma in the reviewed literature and the first described after PTK. Thorough histopathologic and ultrastructural analyses were conducted. RESULTS: The histochemical, immunohistochemical, and electron microscopic findings were consistent with previously reported corneal myxomas. Most of the reported myxomas arising in the cornea presented with a history of prior corneal disease or injury and showed absence or disruption of Bowman layer histopathologically, as was found in our patient. CONCLUSION: The pathogenesis of corneal myxomas involves a reactive process that requires an antecedent affliction, in contrast to the neoplastic mesenchymal histogenesis of myxomas characterized in other parts of the body.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it