Variant Distribution of Skin Lesions in Angiokeratoma Circumscriptum: Report of an Untypical Case
Bibliographic record
Abstract
Angiokeratoma circumscriptum is one of rare skin lesions mainly manifested in hyperkeratotic papules or nodules occurring frequently unilaterally on the foot or leg and most characteristically takes the form of an extensive vascular plaque. Herein, we report an untypical case of angiokeratoma circumscriptum. Different from the typical form of localized extensive vascular plaque and unilaterally location of the foot or distal aspect of the leg, the skin lesions of present case initiated in the left elbow and recently progressed to ipsilateral arm and trunk. In addition, the skin lesions are varied from multiple, discrete papules to confluent, protruding verrucous plaques. The physical and histopathological findings are consistent with a diagnosis of angiokeratoma circumscriptum. The untypical distribution of skin lesions indicates that the forms of angiokeratoma circumscriptum may be varient in clinic. Since present case shares similar appearances in cutaneous vascular lesions (angiokeratomas) with systemic angiokeratoma corporis diffusum (Fabry disease), the difference between the two entities is also discussed. doi:10.4021/jmc664w
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.003 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".