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Record W2010203932 · doi:10.1038/ng.275

Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

2009· article· en· W2010203932 on OpenAlexaff
Mark S. Silverberg, Judy H. Cho, John D. Rioux, Dermot McGovern, Jing Wu, Vito Annese, Jean Paul Achkar, Philippe Goyette, Regan Scott, Wei Xu, M. Michael Barmada, Lambertus Klei, Mark J. Daly, Clara Abraham, Theodore M. Bayless, Fabrizio Bossa, Anne M. Griffiths, Andrew Ippoliti, Raymond Lahaie, Anna Latiano, Pierre Paré, Deborah D. Proctor, Miguel Regueiro, A. Hillary Steinhart, Stephan R. Targan, L. Philip Schumm, Emily O. Kistner, Annette T. Lee, Peter K. Gregersen, Jerome I. Rotter, Steven R. Brant, Kent D. Taylor, Kathryn Roeder, Richard H. Duerr

Bibliographic record

VenueNature Genetics · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsHôpital du Saint-SacrementHôpital Saint-LucHospital for Sick ChildrenPrincess Margaret Cancer CentreMontreal Heart InstituteUniversité LavalUniversité de MontréalUniversity of TorontoMount Sinai Hospital
FundersNational Center for Research ResourcesNational Institute of Diabetes and Digestive and Kidney DiseasesNational Center for Advancing Translational SciencesNational Institute of Mental Health
KeywordsBiologyUlcerative colitisGenome-wide association studyLocus (genetics)Odds ratioGeneticsChromosomeInflammatory bowel diseasePopulationGenomeDiseaseGenotypeInternal medicineSingle-nucleotide polymorphismGeneMedicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.041
Threshold uncertainty score0.986

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.238
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations393
Published2009
Admission routes1
Has abstractno

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