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Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

2006· article· en· 409 citations· W2011001343 on OpenAlex· 10.1016/j.cmet.2006.11.005

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.016
GPT teacher head0.246
Teacher spread
0.230 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Cell Metabolism
Topic
Adipokines, Inflammation, and Metabolic Diseases
Field
Medicine
Canadian institutions
Funders
National Medical Research CouncilNational Health and Medical Research CouncilAustralian Research CouncilCanadian Institutes of Health ResearchNational Institutes of HealthCanadian Diabetes AssociationNational Institute of Diabetes and Digestive and Kidney DiseasesHeart and Stroke Foundation of Canada
Keywords
Insulin resistanceEndocrinologyTumor necrosis factor alphaInternal medicineAMPKInsulin receptorDownregulation and upregulationBiologySkeletal muscleSignal transductionProtein kinase AKinaseInsulinChemistryCell biologyMedicineBiochemistry
Has abstract in OpenAlex
no