MétaCan
Menu
Back to cohort
Record W2011095007 · doi:10.1089/omi.2009.0096

Preliminary Exploration of Time Course DNA Microarray Data with Correlation Maps

2010· article· en· W2011095007 on OpenAlexafffund
Robert M Flight, Peter D. Wentzell

Bibliographic record

VenueOMICS A Journal of Integrative Biology · 2010
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGene expression and cancer classification
Canadian institutionsDalhousie University
FundersNatural Sciences and Engineering Research Council of CanadaMitacs
KeywordsVisualizationCorrelationComputer scienceCourse (navigation)Data visualizationData miningMicroarray analysis techniquesDNA microarrayBiologyGeneGene expressionMathematicsGeneticsEngineering

Abstract

fetched live from OpenAlex

In the analysis of data from high-throughput experiments, information regarding the underlying data structure provides the researcher with confidence in the appropriateness of various analysis methods. One extremely simple but powerful data visualization method is the correlation heat map, whereby correlations between experiments/conditions are calculated and represented using color. In this work, the use of correlation maps to shed light on transcription patterns from DNA microarray time course data prior to gene-level analysis is described. Using three different time course studies from the literature, it is shown how the patterns observed at the array level provide insights into the dynamics of the system under study and the experimental design.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.069
Threshold uncertainty score0.308

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.287
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2010
Admission routes2
Has abstractyes

Explore more

Same venueOMICS A Journal of Integrative BiologySame topicGene expression and cancer classificationFrench-language works237,207