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Record W2011984152 · doi:10.1177/155005940904000411

Spikes and Epilepsy

2009· review· en· W2011984152 on OpenAlexaff
E. Rodin�, T. Constantino, Stefan Rampp, Peter K. H. Wong

Bibliographic record

VenueClinical EEG and Neuroscience · 2009
Typereview
Languageen
FieldMedicine
TopicEpilepsy research and treatment
Canadian institutionsBC Children's Hospital
Fundersnot available
KeywordsIctalElectroencephalographyComputer scienceNeuroscienceScalpEpilepsyPattern recognition (psychology)PhysicsPsychologyArtificial intelligenceMedicineAnatomy

Abstract

fetched live from OpenAlex

Digital EEG analysis provides significantly more information to the clinical electroencephalographer (EEGer) for scalp as well as for intracranial monitoring than is currently being routinely utilized. When modern data analysis software is used, interictal spikes contain considerably more information than had previously been ascribed to them. To optimize the diagnostic value of the EEG, sleep recordings after sleep deprivation is valuable because focal spikes, unless abundant, are relatively rare in the waking state. Recording time should also be sufficiently long to allow spikes to emerge. Spikes are always pathologic and can be associated with impaired cerebral perfusion, metabolic changes and concomitant behavioral changes. They can also be separated into simple and complex forms which may allow prognostic statements. The simplest way to accomplish this is by placing a cursor on the peak of the spike and see whether or not other channels show latency differences. More precise methods are: comparisons of voltage maps with current source density maps, principal component analysis and distinctions between stationary versus moving dipoles. Averaging of spikes is valuable but care must be taken that only those spikes which have the same distribution are averaged, and when the average is obtained only from the spike peak, propagation may already have occurred. It has been recommended that the midpoint of the ascending negative phase be used as the point for averaging. In intracranial recordings the frequencies above the gamma range should also be assessed. Their small electrical field allows a differentiation between locally generated events from those which are volume conducted and can thereby more accurately reflect the epileptogenic zone(s). High frequency activity can also be recorded from foramen ovale electrodes which enhances their diagnostic utility. It is emphasized that for centers which perform pre-surgical evaluations the software supplied by instrument manufacturers is inadequate and needs to be supplemented by additional commercially available programs. Furthermore, archived data should be used for retrospective investigations and follow-up studies of patients who have undergone either excisions, resections, or multiple subpial transections to evaluate the success rates by taking into account all the properties of interictal and ictal recordings which are mentioned in this article.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.997
Threshold uncertainty score0.624

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.225
GPT teacher head0.506
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2009
Admission routes1
Has abstractyes

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