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Record W2012205153 · doi:10.1021/tx000109k

Caspases at the Heart of the Apoptotic Cell Death Pathway

2000· review· en· W2012205153 on OpenAlexaffabout
Sophie Roy

Bibliographic record

VenueChemical Research in Toxicology · 2000
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCell death mechanisms and regulation
Canadian institutionsMerck Canada Inc. (Canada)
Fundersnot available
KeywordsCitationApoptosisCaspaseComputer scienceLibrary scienceIconWorld Wide WebInformation retrievalProgrammed cell deathChemistryBiochemistry

Abstract

fetched live from OpenAlex

ADVERTISEMENT RETURN TO ISSUEPREVOpen ForumNEXTCaspases at the Heart of the Apoptotic Cell Death PathwaySophie RoyView Author Information Department of Biochemistry & Molecular Biology, Merck Frosst Centre for Therapeutic Research, Merck Frosst & Company, 16711 Trans Canada Highway, Kirkland, Québec, Canada H9H 3L1 Cite this: Chem. Res. Toxicol. 2000, 13, 10, 961–962Publication Date (Web):September 29, 2000Publication History Received17 May 2000Published online29 September 2000Published inissue 1 October 2000https://doi.org/10.1021/tx000109kCopyright © 2000 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views219Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (37 KB) Get e-AlertsSUBJECTS:Apoptosis,Cells,Genetics,Monomers,Peptides and proteins Get e-Alerts

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.860
Threshold uncertainty score0.613

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.105
GPT teacher head0.394
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations31
Published2000
Admission routes2
Has abstractyes

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