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Record W2012236063 · doi:10.5430/jbgc.v4n1p47

Mild encephalopathy with reversible lesion of the splenium caused by infectious endocarditis

2013· article· en· W2012236063 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Biomedical Graphics and Computing · 2013
Typearticle
Languageen
FieldMedicine
TopicInfectious Encephalopathies and Encephalitis
Canadian institutionsnot available
Fundersnot available
KeywordsSpleniumMedicineCorpus callosumEncephalopathyFluid-attenuated inversion recoveryAtaxiaLightheadednessPathologyRadiologyCardiologyMagnetic resonance imagingInternal medicineDiffusion MRI

Abstract

fetched live from OpenAlex

Mild encephalopathy with reversible lesion of the splenium of corpus callosum is a rare disease revealing mild neurological symptoms, such as disturbance, ataxia, vertigo and in some cases headache. Magnetic resonance signal alterations in the splenium of the corpus callosum can be found in patients suffering from different diseases, mostly viral infections, but also seizures, antiepileptic drug therapy, bacterial infections, hypoglycaemia, Wernicke encephalopathy, Marchiafava Bignami disease, hemolytic uremic syndrome, acute urinary retention, and acute axonal trauma. We report a 32-year old man admitted to our hospital with fever and vomiting. In the neurological examination he presented with mild dizziness and confusion. Until that time no cardiac symptoms had been reported. Due to the neurological symptoms an MR scan of the brain was performed visualizing an area of restricted diffusion with a diameter of 7 mm located in the central portion of the splenium of the corpus callosum being hyperintense on Fluid Attenuated Inversion Recovery (FLAIR) and T2-weighted turbo spin-echo images. Furthermore, multiple punctate lesions with similar appearance on diffusion weighted imaging were found in both hemispheres suspicious of embolic ischemic etiology. Consecutive transesophageal echocardiography revealed endocarditis of the mitral valve. Transient lesions of the splenium recovering within a month are not specific and there is a wide range of differential diagnoses. They may indicate severe disease despite of initially mild neurological symptoms. Pathophysiology of these lesions is not clearly understood yet, even if there exist some – however not proven – theories, such as rapidly resolving intramyelinic edema or influx of inflammatory cells associated with cytotoxic edema.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.097
Threshold uncertainty score0.310

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.221
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it