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Record W2013125628 · doi:10.1118/1.4740167

Poster — Thur Eve — 59: Dosimetric evaluation on the variation of PTV coverage due to patient size reduction using the prostate dose‐volume factor in prostate radiotherapy

2012· article· en· W2013125628 on OpenAlexaff
J Chow, Ran Jiang, Daniel Markel

Bibliographic record

VenueMedical Physics · 2012
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsPrincess Margaret Cancer Centre
Fundersnot available
KeywordsMedicineNuclear medicineProstateRadiation therapyDosimetryProstate cancerRadiologyCancerInternal medicine

Abstract

fetched live from OpenAlex

We proposed to use the prostate dose‐volume factor (PDVF), derived from the dose‐volume dataset of planning target volume (PTV) in prostate radiotherapy to evaluate treatment plans of prostate volumetric modulated arc therapy (VMAT) and intensity modulated radiotherapy (IMRT). To demonstrate plan evaluation using PDVF, VMAT and 7‐beam IMRT plans were created in three patients with prostate volumes equal to 32, 48.4 and 86.5 cm3. Dose variation of PTV was made by reducing the body contour of the patients with reduced depth equal to 0.5 – 2 cm, mimicking a patient size reduction in the treatment. The Gaussian error function was used to model the cumulative dose‐volume histogram of the PTV, and PDVF was calculated as per the parameters of the error function. PDVF = 1 reflects an ideal PTV coverage (i.e. 100% prescribed dose in 100% target volume). We found that for PDVF ranged 0.98 – 1 in prostate VMAT and IMRT without patient size change, reduced depth led to PDVF decreasing 0.03 ± 4.7 × 10−4 (VMAT) and 0.04 ± 9.7 × 10−3 (IMRT) per cm for the patients. The variation of PTV coverage on the prostate volume due to the reduced depth was less significant in VMAT plans than IMRT. It is concluded that PDVF was successfully used to evaluate the variation of PTV coverage due to the weight loss of patient in prostate VMAT and IMRT. Degradation of PTV coverage in prostate VMAT regarding patient size reduction is less significant than that in IMRT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.302
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

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