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Record W2013349424 · doi:10.1159/000205829

Bone Marrow Cultures in Dysmyelopoietic Syndrome: Diagnostic and Prognostic Evaluation

2009· article· en· W2013349424 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueActa Haematologica · 2009
Typearticle
Languageen
FieldMedicine
TopicAcute Myeloid Leukemia Research
Canadian institutionsMcGill UniversityRoyal Victoria Hospital
Fundersnot available
KeywordsHaematopoiesisProgenitor cellBone marrowAcute leukemiaMyeloid leukemiaPreleukemiaLeukemiaImmunologyBiologyIn vitroMedicineInternal medicineGastroenterologyPathologyStem cellGenetics

Abstract

fetched live from OpenAlex

Thirty-four patients with a probable clinical diagnosis of dysmyelopoietic syndrome (DMPS) were studied to assess the in vitro growth pattern of their hemopoietic progenitors, i.e. burst-forming unit erythroid (BFU-E) and colony-forming unit myeloid (CFU-C) progenitor cells. Twenty-one patients had DMPS confirmed by final diagnosis and were classified according to the French-American-British (FAB) recommendations. Our results indicate that the normal colony growth of hemopoietic progenitors in vitro excludes DMPS and other preleukemic conditions. In addition, within the DMPS group a low number of CFU-C (11 colonies or fewer) was a highly significant indicator for the development of acute leukemia. Analysis of the limited number of cytogenetic results in the DMPS patients did not reach statistical significance in relation to the development of acute leukemia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.247
Threshold uncertainty score0.895

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.321
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it