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Smoking and the Risk of Nonmelanoma Skin Cancer

2012· review· en· W2013980032 on OpenAlexaboutno aff
Jo Leonardi‐Bee, Thomas Ellison, Fiona Bath‐Hextall

Bibliographic record

VenueArchives of Dermatology · 2012
Typereview
Languageen
FieldMedicine
TopicNonmelanoma Skin Cancer Studies
Canadian institutionsnot available
FundersNational Institute for Health and Care ResearchBritish Heart FoundationCancer Research UK
KeywordsMedicineSkin cancerBasal cell carcinomaBasal cellOdds ratioDermatologyMeta-analysisOncologyCancerInternal medicineCarcinoma

Abstract

fetched live from OpenAlex

OBJECTIVE: To perform a systematic review and meta-analysis to collate evidence of the effects of smoking on the risk of nonmelanoma skin cancer. DATA SOURCES: We searched 4 electronic databases (from inception to October 2010) and scanned the reference lists of the publications retrieved to identify eligible comparative epidemiologic studies. STUDY SELECTION: Titles, abstracts, and full text were assessed independently by 2 authors against prespecified inclusion/exclusion criteria. DATA EXTRACTION: Data were extracted and quality was assessed independently by 2 authors using the Newcastle-Ottawa Scale. DATA SYNTHESIS: Meta-analysis was performed using random-effects models. Results are presented as odds ratios (ORs) with 95% CIs. Heterogeneity was assessed using I2. Twenty-five studies were included. Smoking was significantly associated with cutaneous squamous cell carcinoma (OR, 1.52; 95% CI, 1.15-2.01; I2 = 64%; 6 studies). Smoking was not significantly associated with basal cell carcinoma (OR, 0.95; 95% CI, 0.82-1.09; I2 = 59%; 14 studies) or nonmelanoma skin cancer (OR, 0.62; 95% CI, 0.21-1.79; I2 = 34%; 2 studies). CONCLUSION: This study clearly demonstrates that smoking increases the risk of cutaneous squamous cell carcinoma; however, smoking does not appear to modify the risk of basal cell carcinoma.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.027
metaresearch head score (Gemma)0.065
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.027
Threshold uncertainty score0.142

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0270.065
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0140.029
Bibliometrics0.0080.007
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0020.001
Research integrity0.0030.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.323
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations108
Published2012
Admission routes1
Has abstractyes

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