Neurotoxic damage to the dorsomedial striatum exaggerates the behavioral influence of a context-specific inhibitory association mediated by the ventral hippocampus.
Bibliographic record
Abstract
This study investigated the role of the dorsomedial striatum (DMS) on the acquisition of a context-specific inhibitory association acquired during training on a simple visual discrimination task. The authors have previously shown that this inhibitory association depends on the circuitry of the ventral hippocampus. The authors were interested in the anatomical and functional relationship between the hippocampus and DMS and the potential contribution the DMS makes to this inhibitory behavior. Rats with neurotoxic lesions of the DMS, or shams, were assessed on the acquisition of a visual discrimination task. Following asymptotic performance, they were given reversal training in the same or different context from the original training. The results indicated that the rats with DMS damage showed an exaggerated context-specific inhibition effect. The rats with DMS damage were also impaired on a simultaneously trained tactile/spatial discrimination, a functional effect linked to a neural circuit that includes the dorsal hippocampus. A discussion of potential pathways and mechanisms for these different effects is presented.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.002 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.002 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".