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Record W2014236672 · doi:10.1139/v03-106

The extended hyper-Wiener index

2003· article· en· W2014236672 on OpenAlexvenueno aff
X H Li

Bibliographic record

VenueCanadian Journal of Chemistry · 2003
Typearticle
Languageen
FieldComputer Science
TopicComputational Drug Discovery Methods
Canadian institutionsnot available
Fundersnot available
KeywordsWiener indexQuantitative structure–activity relationshipTopological indexRobustness (evolution)Atom (system on chip)ChemistryMathematicsWiener processIndex (typography)CombinatoricsStatisticsStereochemistryComputer science

Abstract

fetched live from OpenAlex

According to the definition of molecular connectivity and the definition of a hyper-Wiener index, a novel set of hyper-Wiener indexes (R n , m R n ) are defined and are named the extended hyper-Wiener indexes. Where n = 1, 2, 3, 4,... represents the type of subgraph units and is the number of endmost atoms of the subgraph unit, m is the number of atoms of the subgraph unit. Here n = 1 means the subgraph unit is an atom, n = 2 means the subgraph units are straight-line combinations of m atoms (m = 2, 3, 4, 5, 6,...), and n = 3 means the subgraph units are Y types of combinations of m atoms (m = 4, 5, 6, 7, 8,...), and so on. The potential usefulness of the extended hyper-Wiener index in QSAR and (or) QSPR is evaluated by its correlation with a number of C 3 –C 8 alkanes and by a favorable comparison with models based on the molecular connectivity index and the overall Wiener index. To verify the robustness and the predictive ability of the models, a cross-validation procedure, leave-one-out, and a random test were also performed. The results show that the extended hyper-Wiener indexes examined demonstrate a good potential for QSAR and QSPR studies. Considerably better statistics are obtained when extending the hyper-Wiener index to the extended hyper-Wiener index. The extended hyper-Wiener indexes provided statistical results as good as the molecular connectivity indexes and the overall Wiener index in all models, and the standard deviations provided by these three sets of indexes are rather close. Moreover, this method may provide a better way to apply the Wiener number and the hyper-Wiener index to the system of unsaturated hydrocarbons and organic compounds, including heteroatoms, according to the method of the molecular connectivity index. This can extend the usefulness of the Wiener number and hyper-Wiener index and can make them a kind of widely used topological index in practice.Key words: hyper-Wiener index (R), extended hyper-Wiener index, molecular connectivity index.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.632
Threshold uncertainty score0.489

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.241
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2003
Admission routes1
Has abstractyes

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