Authentication of Caralluma adscendens var. fimbriata (Wall.) Gravely & Mayur
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
A Phase 2 clinical trial with Black Cohosh and Red Clover was conceived in 2000 within our UIC/NIH Center for Botanical Dietary Supplement Research on Womens Health. Prior to implementing the trial, a Phase 1 study was required and approval from FDA that an IND application was not required since the end point being measured was reduction in hot flashes in menopausal women. Menopause, for purposes of FDA is not considered a disease. The study was delayed for more than a year in order to prepare a botanically authenticated and chemically and biologically standardized extract. It was ascertained that the biological endpoint for purposes of the study would be interaction with certain serotonin receptors, in vitro. The study preparations had to be formulated and were subjected to accelerated stability studies. During the recruitment of suitable subjects the results of the WHI (Womens Health Initiative) caused difficulty in the ability to recruit suitable women since the study had four arms, i.e. Black Cohosh, Red Clover, Placebo and Prempro and many women were reluctant to enter the trial if there was a possibility that there would be taking Prempro. Because of this, only 88 subjects were recruited of the 128 initially planned. However, the study was powered sufficiently if the dropout rate was less than 15 %. In the final analysis, Red Clover was shown to positively affect cognition but neither test preparation reduced hot flashes. A discussion of these results will be presented.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it