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Record W2015534067 · doi:10.1021/om201201h

Geminal Carbon–Hydrogen Bond Activation in Cumulenes Promoted by Adjacent Iridium/Ruthenium Centers

2012· article· en· W2015534067 on OpenAlexafffund
T.J. MacDougall, R.G. Samant, S.J. Trepanier, Michael J. Ferguson, Robert McDonald, Martín Cowie

Bibliographic record

VenueOrganometallics · 2012
Typearticle
Languageen
FieldChemistry
TopicAsymmetric Hydrogenation and Catalysis
Canadian institutionsUniversity of Alberta
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of Alberta
KeywordsChemistryGeminalIridiumRutheniumCarbon–hydrogen bond activationPhotochemistryHydrogenCarbon fibersTriple bondHydrogen bondPolymer chemistryMedicinal chemistryMoleculeCatalysisOrganic chemistryDouble bond

Abstract

fetched live from OpenAlex

The tetracarbonyl complex [IrRu(CO) 4 (dppm) 2 ][BF 4 ] (dppm = μ-Ph 2 PCH 2 PPh 2 ) ( 1 ) reacts with allene and methylallene, resulting in double, geminal carbon–hydrogen bond activation accompanied by H migration, one each to the β- and γ-carbons of the allene, yielding the vinylidene-bridged complexes [IrRu(CO) 4 (μ-C═C(H)R)(dppm) 2 ][BF 4 ] (R = CH 3 ( 2 ), C 2 H 5 ( 3 )). Reaction of 1 with 1,1-dimethylallene results in the activation of the pair of geminal C–H bonds together with one of the methyl C–H bonds, yielding the vinylvinylidene-bridged product [IrRu(CO) 4 (μ-C═C(H)C(CH 3 )═CH 2 )(dppm) 2 ][BF 4 ] ( 4 ), accompanied by H 2 loss. The addition of 1,1-difluoroallene to compound 1 does not lead to C–H activation but instead forms the fluoroallene-bridged adduct [IrRu(CO) 4 (μ-κ 1:κ 1 -F 2 C═ C – C H 2 )(dppm) 2 ][BF 4 ] ( 5 ), bound through the unsubstituted end of the allene and having the CH 2 group bound to Ru. This species rearranges, over 24 h at ambient temperature, to its isomer ( 5a ), having the CH 2 end bound to Ir. Although ethylene and propylene fail to react with 1 at ambient temperature, they react with the tricarbonyl analogue [IrRu(CO) 3 (dppm) 2 ][BF 4 ] ( 8 ) at −20 °C to yield the alkenyl-bridged hydrides [IrRu(CO) 3 (H)(μ-κ 1:η 2 -C(H)═CHR)(dppm) 2 ][BF 4 ] (R = H ( 6 ), CH 3 ( 7 )), by activation of a single C–H bond. Compound 8 reacts similarly with allene at −20 °C, yielding [IrRu(H)(CO) 3 (μ-κ 1:η 2 -CH═C═CH 2 )(dppm) 2 ][BF 4 ] ( 11 ). None of these alkenyl or allenyl hydride species give rise to a second C–H activation upon warming. However, warming 11 in the presence of CO does yield 2, together with decomposition products. Removal of a carbonyl from the vinylidene-bridged complexes [IrRu(CO) 4 (μ-C═C(H)R)(dppm) 2 ][BF 4 ] (R = CH 3 ( 2 ), R = H ( 9 )) generates the alkynyl hydride complexes [IrRu(H)(CO) 3 (μ-κ 1:η 2 -C≡CR)(dppm) 2 ][BF 4 ] (R = CH 3 ( 12 ), H ( 10 )), both of which can be converted back to the respective vinylidenes by CO addition. On the basis of these observations, a mechanism is proposed for the transformations of allene and methylallene into the methyl- and ethylvinylidene-bridged products, noted above.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.041
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.224
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2012
Admission routes2
Has abstractyes

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