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Record W2015660543 · doi:10.1139/z09-110

The effects of feeding on cell morphology and proliferation of the gastrointestinal tract of juvenile Burmese pythons (Python molurus)

2009· article· en· W2015660543 on OpenAlexvenueno aff
Cécile Helmstetter, Robert K. Pope, Mathieu T’Flachebba, Stephen M. Secor, Jean‐Hervé Lignot

Bibliographic record

VenueCanadian Journal of Zoology · 2009
Typearticle
Languageen
FieldMedicine
TopicPancreatic function and diabetes
Canadian institutionsnot available
FundersConseil Régional d'Alsace
KeywordsBiologyStomachGastrointestinal tractSmall intestineLarge intestineInternal medicineEndocrinologyBiochemistry

Abstract

fetched live from OpenAlex

The gastrointestinal tract of Burmese pythons ( Python molurus (L., 1758)) exhibits large morphological and physiological changes in response to feeding and extended periods of fasting. In this study the mucosa of the stomach, small intestine, and colon were examined for changes in structure and cellular proliferation. The mucosa of fasting pythons exhibited low levels of cellular replication, but after feeding, cellular replication was evident as early as 12 h in the small intestine and colon and 24 h in the stomach. Replication peaked 3 days postfeeding for the small intestine and colon, but was still increasing at 6 days postfeeding in the stomach. Interestingly, cell proliferation was still evident after 45 days in the colon. In these tissues, a stock of “ready-to-use” primary lysosomes is found in the mucosal cells of fasting animals, whereas profound intracellular recycling is typical of animals that have been fed. These findings indicate that during the postprandial period, the intestinal mucosa undergoes extensive remodelling in anticipation of the next fasting and feeding period. One key adaptive factor for the python’s ability to cope with infrequent feeding is a well-prepared digestive system in fasting animals that can quickly start functioning again when food becomes available.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.217
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2009
Admission routes1
Has abstractyes

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Same venueCanadian Journal of ZoologySame topicPancreatic function and diabetesFrench-language works237,207