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Record W2015757033 · doi:10.1136/ebm.7.6.183

Oral dexamethasone improved respiratory distress in children <2 years of age with acute bronchiolitis

2002· article· en· W2015757033 on OpenAlexaboutno aff
Peter Wyer

Bibliographic record

VenueEvidence-Based Medicine · 2002
Typearticle
Languageen
FieldMedicine
TopicRespiratory viral infections research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineRespiratory distressBronchiolitisPlaceboDexamethasonePediatricsInternal medicineRespiratory systemSurgery

Abstract

fetched live from OpenAlex

(2002) J Pediatr 140, 27; Schuh S, Coates AL, Binnie R, et al. . Efficacy of oral dexamethasone in outpatients with acute bronchiolitis. . Jan; . : . –32. . [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] QUESTION: In children <2 years of age who present to the emergency department (ED) with acute bronchiolitis, what is the effectiveness of oral dexamethasone? Randomised (allocation concealed*), blinded (clinicians, patients, data collectors, and outcome assessors),* placebo-controlled trial with follow up at 4 hours and 7 days. The ED of a hospital in Toronto, Ontario, Canada. 71 children who were between 8 weeks and 23 months of age, had a first wheezing episode associated with respiratory distress and an upper respiratory tract infection, and had a Respiratory Disease Assessment Instrument rating ≥6. Follow-up was 99% at 4 hours (mean age 6.5 mo, 61% boys) and 94% at 7 days. 36 children were allocated to a single dose of oral dexamethasone, 1 mg/kg, and 34 were allocated to placebo. At 0, 30, 60, and 120 … [1]: {openurl}?query=rft.jtitle%253DThe%2BJournal%2Bof%2Bpediatrics%26rft.stitle%253DJ%2BPediatr%26rft.aulast%253DSchuh%26rft.auinit1%253DS.%26rft.volume%253D140%26rft.issue%253D1%26rft.spage%253D27%26rft.epage%253D32%26rft.atitle%253DEfficacy%2Bof%2Boral%2Bdexamethasone%2Bin%2Boutpatients%2Bwith%2Bacute%2Bbronchiolitis.%26rft_id%253Dinfo%253Adoi%252F10.1067%252Fmpd.2002.120271%26rft_id%253Dinfo%253Apmid%252F11815760%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1067/mpd.2002.120271&link_type=DOI [3]: /lookup/external-ref?access_num=11815760&link_type=MED&atom=%2Febmed%2F7%2F6%2F183.atom [4]: /lookup/external-ref?access_num=000173670000008&link_type=ISI

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Non-randomized triallow
gptno category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Other designhigh
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.252
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.073
GPT teacher head0.350
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designNon-randomized trial · Other design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2002
Admission routes1
Has abstractyes

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