Novel Anti‐Microbial Host‐Guest Complexes Based on Cationic <i>β</i>‐Cyclodextrin Polymers and Triclosan/Butylparaben
Bibliographic record
Abstract
Abstract The preparation of novel cationic β ‐cyclodextrin polymers (CP β CDs) and its complexes with butylparaben and triclosan were reported in this paper. FT‐IR and two‐dimensional (2D) 1 H– 1 H gradient correlated spectroscopy (gCOSY) NMR spectra confirmed that the antibiotics could be included inside the lipophilic cavities of CP β CDs. The water solubility of the antibiotics was improved significantly after inclusion with CP β CDs. The results also suggest that it was easier for butylparaben, which had relatively small molecular size, to form the complexes with CP β CDs than triclosan. Due to the targeting effect after the inclusion with cationic CP β CDs, the anti‐microbial activity of butylparaben was also enhanced substantially. However, similar improvement was not obvious for triclosan. magnified image
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".