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Record W2016225757 · doi:10.1136/jech.2011.142976h.68

P2-32 Vitamin D in the prediction of metabolic syndrome: a target for public health intervention

2011· article· en· W2016225757 on OpenAlexaffabout
Darren R. Brenner, Paul Arora, B. Garica-Bailo, Ahmed El‐Sohemy, Mohamed A. Karmali, Alaa Badawi

Bibliographic record

VenueJournal of Epidemiology & Community Health · 2011
Typearticle
Languageen
FieldEnvironmental Science
TopicHealth, Environment, Cognitive Aging
Canadian institutionsPublic Health OntarioUniversity of TorontoPublic Health Agency of Canada
Fundersnot available
KeywordsMedicineMetabolic syndromeNational Health and Nutrition Examination SurveyNational Cholesterol Education ProgramLogistic regressionReceiver operating characteristicGerontologyPopulationVitamin D and neurologyDemographyEnvironmental healthInternal medicineObesity

Abstract

fetched live from OpenAlex

Background The association between vitamin D (VitD) and cardiometabolic health has been described however the ability of VitD to predict metabolic syndrome (MetSyn) beyond individual demographics and common lifestyle factors is unclear. Methods 1799 adults from the Canadian Health Measures Survey, a nationally representative survey were examined. MetSyn was defined based on the National Cholesterol Education Program's Adult Treatment Panel III criteria. The comparative value of smoking status, energy expenditure from physical activity and plasma 25 (OH)D VitD to predict the presence of metabolic syndrome was evaluated using receiver operating characteristic curves (ROC) from fully adjusted logistic regression models (age, sex, ethnicity, education, annual fruit intake and month of interview). Somer's D and c statistics were used to compare across models. Sampling weights were applied to all models. Results Inclusion of plasma VitD, energy expenditure and smoking status all lead to increases in the c statistic and Somer's D suggesting increased predictive ability compared to the baseline model. ROC contrasts, however, showed that only inclusion of VitD significantly increased the predictive ability of the model (p=0.001). Discussion VitD may be a useful predictive tool for cardiometabolic risk prediction in addition to conventional factors. Prospective analyses may provide more insight into VitD as a potential population-based intervention target for reduction of chronic disease burden related to MetSyn.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.065
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.063
Threshold uncertainty score0.994

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0650.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.201
GPT teacher head0.373
Teacher spread0.172 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes2
Has abstractyes

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