Neonatal group B streptococcal disease: Incidence, presentation, and mortality
Bibliographic record
Abstract
OBJECTIVES: To ascertain the incidence, and compare the clinical characteristics, laboratory parameters, and immediate mortality of neonates with early-onset (symptomatic and asymptomatic) and late-onset group B streptococcal (GBS) disease. METHODS: A chart review of 81 neonates with GBS disease (either blood and/or cerebrospinal fluid culture-proven) born between 1995 and 2002 admitted to two tertiary care perinatal centers in Toronto was conducted. Clinical characteristics were compared for (1) asymptomatic early-onset, symptomatic early-onset, and late-onset GBS disease and (2) survivors and non-survivors. RESULTS: The incidence of GBS disease was 1.13/1000 live births. One or more antepartum or intrapartum predisposing factors were recognized in 62% of cases. Early-onset was noted in 65 (80%) neonates (23 asymptomatic and 42 symptomatic). All full-term infants survived. The mortality was 6% and was confined to preterm neonates with early symptomatic disease who presented with shock and had thrombocytopenia. CONCLUSION: Antepartum or intrapartum known predisposing risk factors of GBS disease were lacking in one third of patients. Patients who died were preterm infants in the early symptomatic group.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".